We are interested in interconnecting medical standpoints with basic research concepts to ask relevant scientific questions. As an MD/PhD, I have the training and experience to approach these questions from both clinical and basic science perspectives. I acquired clinical experience treating patients as a clinical immunologist in Brazil and in the US as a clinical embryologist at UNC. My PhD training was in Immunology. During my post-doctoral work at NIEHS-NIH in Dr. Perry Blackshear lab, using genetically-engineered mouse models, my findings led me to the intriguing field of reproductive biology and female infertility. We brought this new research endeavor implicating the role of Zinc Finger Protein 36 Like 2 (ZFP36L2, “L2”) an RNA-binding protein in mouse infertility to set up an independent research program at UNC-CH. My research is focused on RNA-binding proteins and their physiopathological roles in vivo. I have a broad medical and biochemical background, with specific training and expertise in RNA-binding proteins and the creation of genetically-engineered mouse models. As a biochemistry, I aim to identify novel mRNA targets for RNA-binding proteins and as an MD I aspire to better understand mechanistically how RNA binding proteins are involved in pathological condition. Being a PI or co-Investigator or Key Personnel on university- and NIH-funded grants, I laid the groundwork for examining the role of ZFP36L2 in vivo and I made several key new findings during my K08 award (2012-2017). I have unveiled the role of ZFP36L2 in early embryo development and infertility, but also expanded my studies in the structural basis of ZFP36L2-mRNA interactions and to other physiological contexts in which ZFP36L2 has a crucial role, such as in T cells and spleen function. This new direction in understanding how ZFP36L2 functions at a broader level has naturally developed due to the fact that UNC is a hub for RNA biochemistry fostering internal and outside collaborations that resulted in several peer-reviewed publications.