Advancing Team Science through Translational Research Summits
COHA Clinician Scientist Education Subcommittee
Lead: University Wisconsin-Madison
Partners: Cornell University, Colorado State University, and University of California- Davis
This pilot grant supported a first-of-its-kind Translational Research Summit, with the goal of networking among veterinarians, human health professionals, and basic scientists working on the same disease. The first Summit, on Calcium Oxalate urolithiasis, was held in Madison WI in April 2017. There were 36 attendees, including 14 DVMs, 8 MDs, 12 PhD or MS scientists, and 2 MD/PhD students. Sessions included human and veterinary phenotypes of calcium oxalate stones; genetic risk factors in humans, dogs, and cats; nutritional factors; pathogenesis of mineralization; and endoscopic and histopathologic features across species. The Summit also included abstracts and breakout groups to discuss shared research objectives and potential collaborations.
Development of Standard Processes and Procedures for Conducting Translational Clinical Trials in Client Owned Animals
COHA Clinical Studies Subcommittee
Lead: The Ohio State University
Partners: University of Minnesota, University of Pennsylvania, University of California-Davis, Tufts University
This pilot developed a specific set of practices and procedures for the conduct of translational and comparative clinical trials, with the ultimate goal of ensuring accurate and reproducible data. The group completed a survey of practices and procedures, and published a white paper and generated a veterinary GCP training module. A workshop that brought together faculty and staff from 13 academic veterinary centers, industry sponsors and relevant stakeholders from human medicine, held in Columbus OH in October 2017, also trained staff and faculty in the use of REDCap, and created a template for a veterinary IRB process, including a standardized consent form.
One Health in a Minute
COHA Communication and Collaboration Subcommittee
Lead: Tufts University
Partners: University of Florida, North Carolina State University, University of Pennsylvania
This pilot grant supported identification of One Health stories from interdisciplinary teams at COHA institutions, and development into COHA-branded One Health videos on chronic pain, hypertrophic cardiomyopathy, and the Knight’s Landing One Health Clinic that provides care to both pets and their owners by teams of veterinary, nursing, and medical students. The group also developed the COHA logo, and established a dedicated COHA website (https://ctsaonehealthalliance.org), which also hosts the videos.
Developing a national veterinary biorepository registry as a resource for translational research
COHA Tissue and DNA Banking Subcommittee
Lead: Colorado State University
Partners: Cornell University, University of California Davis
This pilot grant supported a working group meeting in June 2016 to define the state of biorepository registries that currently exist, and develop a plan moving forward. The meeting was successful in enhancing an understanding of different approaches to biobanking at the COHA veterinary institutions present and reinforced the idea that a physical biobank was not an appropriate goal for COHA.